TY - PAT T1 - Apparatus and method for analyzing a sample Y1 - 2021 A1 - Markelz, Andrea G A1 - Acbas, Gheorghe A1 - Niessen, Katherine A. AB -
An apparatus and method for Crystal Anisotropy Terahertz Microscopy (“CATM”) is provided. The apparatus includes an emitter configured to emit a THz pulse and a detector configured to detect the THz pulse after the pulse is transmitted through a sample disposed on a sample surface of the detector. A pulsed radiation generator generates a probe beam to interrogate the detector. The detector may include an electro-optical (“EO”) crystal configured to change in birefringence according to the THz pulse. The sample surface of the detector may have a dielectric coating which is transmissive to THz and reflective to the probe beam. The sample is disposed on the dielectric coating.
PB - USPTO CY - United States UR - https://patents.google.com/patent/US11125685B2/en ER - TY - JOUR T1 - Protein and RNA dynamical fingerprinting JF - Nature communications Y1 - 2019 A1 - Niessen, Katherine A A1 - Xu, Mengyang A1 - George, Deepu K A1 - Chen, Michael C A1 - Ferré-D’Amaré, Adrian R A1 - Snell, Edward H A1 - Cody, Vivian A1 - Pace, James A1 - Schmidt, Marius A1 - Markelz, Andrea G VL - 10 SN - 2041-1723 ER - TY - Generic T1 - Terahertz Light Fingerprints Biomolecular Dynamics T2 - CLEO: Science and Innovations Y1 - 2018 A1 - Deng, Yanting A1 - Xu, Mengyang A1 - Niessen, Katherine A A1 - George, Deepu Koshy A1 - Markelz, Andrea G JF - CLEO: Science and Innovations PB - Optical Society of America ER - TY - JOUR T1 - Moving in the right direction: protein vibrations steering function JF - Biophysical Journal Y1 - 2017 A1 - Niessen, Katherine A A1 - Xu, Mengyang A1 - Paciaroni, Alessandro A1 - Orecchini, Andrea A1 - Snell, Edward H A1 - Markelz, Andrea G VL - 112 SN - 0006-3495 ER - TY - JOUR T1 - Photoactive yellow protein terahertz response: hydration, heating and intermediate states JF - IEEE Transactions on Terahertz Science and Technology Y1 - 2013 A1 - George, Deepu K A1 - Knab, Joseph R A1 - He, Yunfen A1 - Kumauchi, Masato A1 - Birge, Robert R A1 - Hoff, Wouter D A1 - Markelz, Andrea G VL - 3 SN - 2156-342X ER - TY - JOUR T1 - Improved mode assignment for molecular crystals through anisotropic terahertz spectroscopy JF - The Journal of Physical Chemistry A Y1 - 2012 A1 - Singh, Rohit A1 - George, Deepu Koshy A1 - Benedict, Jason B A1 - Korter, Timothy M A1 - Markelz, Andrea G VL - 116 SN - 1089-5639 ER - TY - JOUR T1 - Terahertz magneto-optical polarization modulation spectroscopy JF - JOSA BJOSA B Y1 - 2012 A1 - George, Deepu K A1 - Stier, Andreas V A1 - Ellis, Chase T A1 - McCombe, Bruce D A1 - Černe, John A1 - Markelz, Andrea G VL - 29 SN - 1520-8540 ER - TY - JOUR T1 - Terahertz spectroscopic analysis of peptides and proteins JF - Journal of Infrared, Millimeter, and Terahertz Waves Y1 - 2012 A1 - Falconer, Robert J A1 - Markelz, Andrea G VL - 33 SN - 1866-6892 ER - TY - JOUR T1 - Evidence of protein collective motions on the picosecond timescale JF - Biophysical Journal Y1 - 2011 A1 - He, Yunfen A1 - Chen, J-Y A1 - Knab, Joseph R A1 - Zheng, Wenjun A1 - Markelz, Andrea G VL - 100 SN - 0006-3495 ER - TY - Generic T1 - The role of structure in the protein dynamical transition T2 - 2008 33rd International Conference on Infrared, Millimeter and Terahertz Waves Y1 - 2008 A1 - He, Yunfen A1 - Markelz, Andrea G JF - 2008 33rd International Conference on Infrared, Millimeter and Terahertz Waves PB - IEEE SN - 1424421195 ER - TY - JOUR T1 - Terahertz dielectric sensitivity to biomolecular structure and function JF - IEEE Journal of Selected Topics in Quantum Electronics Y1 - 2008 A1 - Markelz, Andrea G VL - 14 SN - 1077-260X ER - TY - JOUR T1 - Terahertz measurements of protein relaxational dynamics JF - Proceedings of the IEEE Y1 - 2007 A1 - Knab, Joseph R A1 - Chen, Jing-Yin A1 - He, Yunfen A1 - Markelz, Andrea G VL - 95 SN - 0018-9219 ER - TY - Generic T1 - Protein conformational dynamics measured with terahertz time domain spectroscopy T2 - 2006 Joint 31st International Conference on Infrared Millimeter Waves and 14th International Conference on Teraherz Electronics Y1 - 2006 A1 - Knab, Joseph R A1 - Chen, Jing-Yin A1 - Ye, Shuji A1 - He, Yunfen A1 - Markelz, Andrea G JF - 2006 Joint 31st International Conference on Infrared Millimeter Waves and 14th International Conference on Teraherz Electronics PB - IEEE SN - 1424403995 ER - TY - Generic T1 - Tagless and universal biosensor for point detection of pathogens T2 - Terahertz for military and security applications Ii Y1 - 2004 A1 - Markelz, Andrea G A1 - Knab, Joseph R A1 - Chen, Jing-Yin A1 - Černe, John A1 - Cox, William A JF - Terahertz for military and security applications Ii PB - International Society for Optics and Photonics VL - 5411 ER - TY - JOUR T1 - Terahertz applications to biomolecular sensing JF - International Journal of High Speed Electronics and Systems Y1 - 2003 A1 - Markelz, Andrea G A1 - Whitmire, Scott E VL - 13 SN - 0129-1564 ER -