TY - Generic T1 - Measuring phonons in protein crystals T2 - Ultrafast Phenomena and Nanophotonics Xvii Y1 - 2013 A1 - Acbas, G. A1 - Niessen, K. A. A1 - George, D. K. A1 - Snell, E. A1 - Markelz, A. G. ED - Betz, M. ED - Elezzabi, A. Y. ED - Song, J. J. ED - Tsen, K. T. KW - correlated motions KW - dynamics KW - mode KW - molecular crystals KW - molecular vibrations KW - normal modes KW - phonons KW - protein dynamics KW - spectroscopy KW - Terahertz AB -
Using Terahertz near field microscopy we find orientation dependent narrow band absorption features for lysozyme crystals. Here we discuss identification of protein collective modes associated with the observed features. Using normal mode calculations we find good agreement with several of the measured features, suggesting that the modes arise from internal molecular motions and not crystal phonons. Such internal modes have been associated with protein function.
JF - Ultrafast Phenomena and Nanophotonics Xvii T3 - Proceedings of SPIE PB - Spie-Int Soc Optical Engineering CY - Bellingham VL - 8623 SN - 978-0-8194-9392-7 N1 - ISI Document Delivery No.: BGG42