%0 Patent
%D 2021
%T Apparatus and method for analyzing a sample
%A Markelz, Andrea G
%A Acbas, Gheorghe
%A Niessen, Katherine A.
%X
An apparatus and method for Crystal Anisotropy Terahertz Microscopy (“CATM”) is provided. The apparatus includes an emitter configured to emit a THz pulse and a detector configured to detect the THz pulse after the pulse is transmitted through a sample disposed on a sample surface of the detector. A pulsed radiation generator generates a probe beam to interrogate the detector. The detector may include an electro-optical (“EO”) crystal configured to change in birefringence according to the THz pulse. The sample surface of the detector may have a dielectric coating which is transmissive to THz and reflective to the probe beam. The sample is disposed on the dielectric coating.
%I USPTO
%C United States
%G eng
%U https://patents.google.com/patent/US11125685B2/en
%0 Journal Article
%J Nature communications
%D 2019
%T Protein and RNA dynamical fingerprinting
%A Niessen, Katherine A
%A Xu, Mengyang
%A George, Deepu K
%A Chen, Michael C
%A Ferré-D’Amaré, Adrian R
%A Snell, Edward H
%A Cody, Vivian
%A Pace, James
%A Schmidt, Marius
%A Markelz, Andrea G
%B Nature communications
%V 10
%P 1-10
%@ 2041-1723
%G eng
%R https://doi.org/10.1038/s41467-019-08926-3
%0 Conference Proceedings
%B CLEO: Science and Innovations
%D 2018
%T Terahertz Light Fingerprints Biomolecular Dynamics
%A Deng, Yanting
%A Xu, Mengyang
%A Niessen, Katherine A
%A George, Deepu Koshy
%A Markelz, Andrea G
%B CLEO: Science and Innovations
%I Optical Society of America
%P SW3D. 5
%G eng
%R https://doi.org/10.1364/CLEO_SI.2018.SW3D.5
%0 Journal Article
%J Biophysical Journal
%D 2017
%T Moving in the right direction: protein vibrations steering function
%A Niessen, Katherine A
%A Xu, Mengyang
%A Paciaroni, Alessandro
%A Orecchini, Andrea
%A Snell, Edward H
%A Markelz, Andrea G
%B Biophysical Journal
%V 112
%P 933-942
%@ 0006-3495
%G eng
%R https://doi.org/10.1016/j.bpj.2016.12.049
%0 Journal Article
%J IEEE Transactions on Terahertz Science and Technology
%D 2013
%T Photoactive yellow protein terahertz response: hydration, heating and intermediate states
%A George, Deepu K
%A Knab, Joseph R
%A He, Yunfen
%A Kumauchi, Masato
%A Birge, Robert R
%A Hoff, Wouter D
%A Markelz, Andrea G
%B IEEE Transactions on Terahertz Science and Technology
%V 3
%P 288-294
%@ 2156-342X
%G eng
%R https://doi.org/10.1109/TTHZ.2013.2256233
%0 Journal Article
%J The Journal of Physical Chemistry A
%D 2012
%T Improved mode assignment for molecular crystals through anisotropic terahertz spectroscopy
%A Singh, Rohit
%A George, Deepu Koshy
%A Benedict, Jason B
%A Korter, Timothy M
%A Markelz, Andrea G
%B The Journal of Physical Chemistry A
%V 116
%P 10359-10364
%@ 1089-5639
%G eng
%R https://doi.org/10.1021/jp307288r
%0 Journal Article
%J JOSA BJOSA B
%D 2012
%T Terahertz magneto-optical polarization modulation spectroscopy
%A George, Deepu K
%A Stier, Andreas V
%A Ellis, Chase T
%A McCombe, Bruce D
%A Černe, John
%A Markelz, Andrea G
%B JOSA BJOSA B
%V 29
%P 1406-1412
%@ 1520-8540
%G eng
%R https://doi.org/10.1364/JOSAB.29.001406
%0 Journal Article
%J Journal of Infrared, Millimeter, and Terahertz Waves
%D 2012
%T Terahertz spectroscopic analysis of peptides and proteins
%A Falconer, Robert J
%A Markelz, Andrea G
%B Journal of Infrared, Millimeter, and Terahertz Waves
%V 33
%P 973-988
%@ 1866-6892
%G eng
%R https://doi.org/10.1007/s10762-012-9915-9
%0 Journal Article
%J Biophysical Journal
%D 2011
%T Evidence of protein collective motions on the picosecond timescale
%A He, Yunfen
%A Chen, J-Y
%A Knab, Joseph R
%A Zheng, Wenjun
%A Markelz, Andrea G
%B Biophysical Journal
%V 100
%P 1058-1065
%@ 0006-3495
%G eng
%R https://dx.doi.org/10.1016%2Fj.bpj.2010.12.3731
%0 Conference Proceedings
%B 2008 33rd International Conference on Infrared, Millimeter and Terahertz Waves
%D 2008
%T The role of structure in the protein dynamical transition
%A He, Yunfen
%A Markelz, Andrea G
%B 2008 33rd International Conference on Infrared, Millimeter and Terahertz Waves
%I IEEE
%P 1-3
%@ 1424421195
%G eng
%R https://doi.org/10.1109/ICIMW.2008.4665800
%0 Journal Article
%J IEEE Journal of Selected Topics in Quantum Electronics
%D 2008
%T Terahertz dielectric sensitivity to biomolecular structure and function
%A Markelz, Andrea G
%B IEEE Journal of Selected Topics in Quantum Electronics
%V 14
%P 180-190
%@ 1077-260X
%G eng
%R https://doi.org/10.1109/JSTQE.2007.913424
%0 Journal Article
%J Proceedings of the IEEE
%D 2007
%T Terahertz measurements of protein relaxational dynamics
%A Knab, Joseph R
%A Chen, Jing-Yin
%A He, Yunfen
%A Markelz, Andrea G
%B Proceedings of the IEEE
%V 95
%P 1605-1610
%@ 0018-9219
%G eng
%R 10.1109/JPROC.2007.898906
%0 Conference Proceedings
%B 2006 Joint 31st International Conference on Infrared Millimeter Waves and 14th International Conference on Teraherz Electronics
%D 2006
%T Protein conformational dynamics measured with terahertz time domain spectroscopy
%A Knab, Joseph R
%A Chen, Jing-Yin
%A Ye, Shuji
%A He, Yunfen
%A Markelz, Andrea G
%B 2006 Joint 31st International Conference on Infrared Millimeter Waves and 14th International Conference on Teraherz Electronics
%I IEEE
%P 183-183
%@ 1424403995
%G eng
%R https://doi.org/10.1088/0031-9155/47/21/318
%0 Conference Proceedings
%B Terahertz for military and security applications Ii
%D 2004
%T Tagless and universal biosensor for point detection of pathogens
%A Markelz, Andrea G
%A Knab, Joseph R
%A Chen, Jing-Yin
%A Černe, John
%A Cox, William A
%B Terahertz for military and security applications Ii
%I International Society for Optics and Photonics
%V 5411
%P 182-186
%G eng
%R https://doi.org/10.1117/12.563613
%0 Journal Article
%J International Journal of High Speed Electronics and Systems
%D 2003
%T Terahertz applications to biomolecular sensing
%A Markelz, Andrea G
%A Whitmire, Scott E
%B International Journal of High Speed Electronics and Systems
%V 13
%P 951-967
%@ 0129-1564
%G eng
%R https://doi.org/10.1142/S0129156403002101