<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Chen, J. Y.</style></author><author><style face="normal" font="default" size="100%">Knab, J. R.</style></author><author><style face="normal" font="default" size="100%">Cerne, J.</style></author><author><style face="normal" font="default" size="100%">Markelz, A. G.</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Large oxidation dependence observed in terahertz dielectric response for cytochrome c</style></title><secondary-title><style face="normal" font="default" size="100%">Physical Review E</style></secondary-title><alt-title><style face="normal" font="default" size="100%">Phys. Rev. E</style></alt-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">absorption</style></keyword><keyword><style  face="normal" font="default" size="100%">binding</style></keyword><keyword><style  face="normal" font="default" size="100%">conformation</style></keyword><keyword><style  face="normal" font="default" size="100%">dna</style></keyword><keyword><style  face="normal" font="default" size="100%">dynamics</style></keyword><keyword><style  face="normal" font="default" size="100%">heart ferricytochrome-c</style></keyword><keyword><style  face="normal" font="default" size="100%">modes</style></keyword><keyword><style  face="normal" font="default" size="100%">Physics</style></keyword><keyword><style  face="normal" font="default" size="100%">protein flexibility</style></keyword><keyword><style  face="normal" font="default" size="100%">spectroscopy</style></keyword><keyword><style  face="normal" font="default" size="100%">state</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2005</style></year><pub-dates><date><style  face="normal" font="default" size="100%">Oct</style></date></pub-dates></dates><number><style face="normal" font="default" size="100%">4</style></number><volume><style face="normal" font="default" size="100%">72</style></volume><pages><style face="normal" font="default" size="100%">4</style></pages><isbn><style face="normal" font="default" size="100%">1539-3755</style></isbn><language><style face="normal" font="default" size="100%">English</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;Far infrared dielectric response is used to characterize the collective mode density of states for cytochrome c as a function of oxidation state and hydration using terahertz time domain spectroscopy. A strong absorbance and refractive index increase was observed with the oxidation. A simple phenomenological fitting using a continuous distribution of oscillators reproduces the frequency dependence of the complex dielectric response as well as demonstrates quantitative agreement with a uniform increase in either mode density or polarizability with oxidation in the 5-80 cm(-1) frequency range. Hydration dependence measurements find that a difference in the equilibrium water content for ferri and ferro cytochrome c is not sufficient to account for the large change in terahertz response. The large dielectric increase at terahertz frequencies with oxidation suggests either a significant global softening of the potential and/or a significant increase in polarizability with oxidation.&lt;/p&gt;</style></abstract><work-type><style face="normal" font="default" size="100%">Article</style></work-type><accession-num><style face="normal" font="default" size="100%">WOS:000232930600005</style></accession-num><notes><style face="normal" font="default" size="100%">ISI Document Delivery No.: 979GO&lt;br/&gt;Times Cited: 51&lt;br/&gt;Cited Reference Count: 29&lt;br/&gt;Cited References: &lt;br/&gt;     BERGHUIS AM, 1992, J MOL BIOL, V223, P959, DOI 10.1016/0022-2836(92)90255-I&lt;br/&gt;     BONE S, 1985, J MOL BIOL, V181, P323, DOI 10.1016/0022-2836(85)90096-8&lt;br/&gt;     BONE S, 1982, J MOL BIOL, V157, P571, DOI 10.1016/0022-2836(82)90477-6&lt;br/&gt;     BROOKS B, 1985, P NATL ACAD SCI USA, V82, P4995, DOI 10.1073/pnas.82.15.4995&lt;br/&gt;     Brucherseifer M, 2000, APPL PHYS LETT, V77, P4049, DOI 10.1063/1.1332415&lt;br/&gt;     Carlson HA, 2002, CURR OPIN CHEM BIOL, V6, P447, DOI 10.1016/S1367-5931(02)00341-1&lt;br/&gt;     CHEN JY, IN PRESS BIOPHYS J&lt;br/&gt;     CUSACK S, 1986, PHYSICA B &amp; C, V136, P256, DOI 10.1016/S0378-4363(86)80069-9&lt;br/&gt;     EDEN D, 1982, P NATL ACAD SCI-BIOL, V79, P815, DOI 10.1073/pnas.79.3.815&lt;br/&gt;     FROHWIRT EM, 1959, BIOPHYS J, V71, P570&lt;br/&gt;     Jackson J.D., 1975, CLASSICAL ELECTRODYN&lt;br/&gt;     KOPPENOL WH, 1982, J BIOL CHEM, V257, P4426&lt;br/&gt;     Kutteruf MR, 2003, CHEM PHYS LETT, V375, P337, DOI 10.1016/S0009-2614(03)00856-X&lt;br/&gt;     Markelz A, 2002, PHYS MED BIOL, V47, P3797, DOI 10.1088/0031-9155/47/21/318&lt;br/&gt;     Markelz AG, 2000, CHEM PHYS LETT, V320, P42, DOI 10.1016/S0009-2614(00)00227-X&lt;br/&gt;     Menikh A, 2004, BIOSENS BIOELECTRON, V20, P658, DOI 10.1016/j.bios.2004.03.006&lt;br/&gt;     Nagel M, 2002, APPL PHYS LETT, V80, P154, DOI 10.1063/1.1428619&lt;br/&gt;     PETHIG R, 1979, DIELECTRIC ELECTRONI&lt;br/&gt;     Qi PXR, 1996, BIOCHEMISTRY-US, V35, P12275, DOI 10.1021/bi961042w&lt;br/&gt;     RINGE D, 1985, PROG BIOPHYS MOL BIO, V45, P197, DOI 10.1016/0079-6107(85)90002-1&lt;br/&gt;     SHECHTER E, 1967, BIOPOLYMERS, V5, P788, DOI 10.1002/bip.1967.360050812&lt;br/&gt;     SIMONSON T, 1995, P NATL ACAD SCI USA, V92, P1082, DOI 10.1073/pnas.92.4.1082&lt;br/&gt;     SREENATHAN BR, 1971, BIOCHEM BIOPH RES CO, V42, P1122, DOI 10.1016/0006-291X(71)90021-0&lt;br/&gt;     Takano T., 1984, Methods and Applications in Crystallographic Computing. 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